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Catalog Number: |
35458 |
| other_names: | AF-1P antibody; AF1P antibody; MLLT5 antibody; EPS15 antibody; ALL1 fused gene from chromosome 1 antibody; epidermal growth factor receptor substrate 15 antibody; protein AF-1p antibody; epidermal growth factor receptor pathway substrate 15 antibody |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:P42566; |
Form of Antibody: |
Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Storage/Stability: |
|
Immunogen: |
Synthetic peptide corresponding to a region within amino acids 832 and 896 of Eps15. |
Purification: |
Antibodies were purified by antigen-affinity chromatography. |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total Eps15 protein. |
Applications: |
WB |
Background: |
This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq] |
References: |
|
appl_detail: |
Western blotting: 1:500-1:3000 |
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