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Eps15 Antibody

Catalog Number:

35458
other_names: AF-1P antibody; AF1P antibody; MLLT5 antibody; EPS15 antibody; ALL1 fused gene from chromosome 1 antibody; epidermal growth factor receptor substrate 15 antibody; protein AF-1p antibody; epidermal growth factor receptor pathway substrate 15 antibody

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P42566;
NCBI Gene#:2060

Form of Antibody:

Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region within amino acids 832 and 896 of Eps15.

Purification:

Antibodies were purified by antigen-affinity chromatography.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Eps15 protein.

Applications:

WB

Background:

This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq]

References:

appl_detail:

Western blotting: 1:500-1:3000

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