Product Datasheet
Eps15 Antibody
Catalog Number: 35458
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P42566;
NCBI Gene#:2060
- Form of Antibody:
- Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Synthetic peptide corresponding to a region within amino acids 832 and 896 of Eps15.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- AF-1P antibody; AF1P antibody; MLLT5 antibody; EPS15 antibody; ALL1 fused gene from chromosome 1 antibody; epidermal growth factor receptor substrate 15 antibody; protein AF-1p antibody; epidermal growth factor receptor pathway substrate 15 antibody
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total Eps15 protein.
- Background:
- This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq]
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