BLM Antibody

Catalog Number:

35370

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P54132;
NCBI Gene#:641

Form of Antibody:

Rabbit IgG in 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage/Stability:

Immunogen:

Recombinant fragment corresponding to a region within amino acids 30 and 385 of BLM.

Purification:

Antibodies were purified by antigen-affinity chromatography.

Specificity/Sensitivity:

The antibody detects endogenous levels of total BLM protein.

Applications:

IF WB

Background:

The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination. [provided by RefSeq]

References:

appl_detail:

Western blotting: 1:500-1:3000
Immunofluorescence: 1:100-1:1000

Datasheet PDF