Product Datasheet
BLM Antibody
Catalog Number: 35370
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P54132;
NCBI Gene#:641
- Form of Antibody:
- Rabbit IgG in 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment corresponding to a region within amino acids 30 and 385 of BLM.
- appl_detail:
- Western blotting: 1:500-1:3000
Immunofluorescence: 1:100-1:1000
- other_names:
- BS antibody; MGC126616 antibody; MGC131618 antibody; MGC131620 antibody; RECQ2 antibody; RECQL2 antibody; RECQL3 antibody; BLM antibody; "DNA helicase; RecQ-like type 2 antibody"; Bloom syndrome protein antibody; recQ protein-like 3 antibody; "Bloom syndr
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total BLM protein.
- Background:
- The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination. [provided by RefSeq]
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