Adenosine Deaminase Antibody

Catalog Number:

35369

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P56658;
NCBI Gene#:100

Form of Antibody:

Rabbit IgG in 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage/Stability:

Immunogen:

Recombinant fragment contain a sequence corresponding to a region within amino acids 119 and 363 of Adenosine Deaminase.

Purification:

Antibodies were purified by antigen-affinity chromatography.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Adenosine Deaminase protein.

Applications:

WB

Background:

This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia. [provided by RefSeq]

References:

appl_detail:

Western blotting: 1:500-1:3000

Datasheet PDF