Product Datasheet
Adenosine Deaminase Antibody
Catalog Number: 35369
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P56658;
NCBI Gene#:100
- Form of Antibody:
- Rabbit IgG in 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment contain a sequence corresponding to a region within amino acids 119 and 363 of Adenosine Deaminase.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- ADA antibody; adenosine aminohydrolase antibody; adenosine deaminase antibody
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total Adenosine Deaminase protein.
- Background:
- This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia. [provided by RefSeq]
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