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MSH2 Antibody

Catalog Number:

35358
other_names: COCA1 antibody; FCC1 antibody; HNPCC antibody; HNPCC1 antibody; LCFS2 antibody; MSH2 antibody; DNA mismatch repair protein Msh2 antibody; mutS protein homolog 2 antibody; hMSH2 antibody; "mutS homolog 2; colon cancer; nonpolyposis type 1 (E. coli) antibod

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P43246;
NCBI Gene#:4436

Form of Antibody:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

A synthesized peptide of human Angiopoietin 2

Purification:

Antibodies were purified by antigen-affinity chromatography.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MSH2 protein.

Applications:

WB

Background:

MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. [provided by RefSeq]

References:

appl_detail:

Western blotting: 1:500-1:2000
 

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