Product Datasheet
MSH2 Antibody
Catalog Number: 35358
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P43246;
NCBI Gene#:4436
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- A synthesized peptide of human Angiopoietin 2
- other_names:
- COCA1 antibody; FCC1 antibody; HNPCC antibody; HNPCC1 antibody; LCFS2 antibody; MSH2 antibody; DNA mismatch repair protein Msh2 antibody; mutS protein homolog 2 antibody; hMSH2 antibody; "mutS homolog 2; colon cancer; nonpolyposis type 1 (E. coli) antibod
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total MSH2 protein.
- Background:
MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. [provided by RefSeq]
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