Smad1/Smad5/Smad8 Antibody

Catalog Number:

21684

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q15797
Gene ID:4086

Form of Antibody:

Storage/Stability:

Immunogen:

Peptide sequence around aa.461-465(I-S-S-V-S) derived from Human Smad1. This sequence has the same homology in Smad5 and Smad8.

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total Smad1, Smad5, Smad8 protein.

Applications:

WB

Background:

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD9 is a receptor-regulated SMAD (R-SMAD). Has been shown to be activated by activin type I receptor-like kinases (ALK-2, ALK-3, ALK-6) which stimulate heteromerization between SMAD9 and SMAD4. May play a role in osteoblast differentiation and maturation.

References:

appl_detail:

Predicted MW: 60kd
Western blotting: 1: 500~1: 1000

Datasheet PDF