Product Datasheet  
Smad1/Smad5/Smad8 Antibody  
Catalog Number: 21684  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q15797
    Gene ID:4086
  • Form of Antibody：  
  • Storage：  
  • Immunogen：  
  • Peptide sequence around aa.461-465(I-S-S-V-S) derived from Human Smad1. This sequence has the same homology in Smad5 and Smad8.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Predicted MW: 60kd
    Western blotting: 1: 500~1: 1000
  • other_names：  
  • Mad-related protein 1, SMAD 1, hSMAD1, Transforming growth factor-beta-signaling protein 1,
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total Smad1, Smad5, Smad8 protein.
  • Applications：  
  • WB
  • Background：  
  • Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD9 is a receptor-regulated SMAD (R-SMAD). Has been shown to be activated by activin type I receptor-like kinases (ALK-2, ALK-3, ALK-6) which stimulate heteromerization between SMAD9 and SMAD4. May play a role in osteoblast differentiation and maturation.



 
© Signalway Biotechnology All Rights Reserved.