TOLLIP Antibody

Catalog Number:

35328

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9H0E2
NCBI Gene ID: 54472

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from Internal of human TOLLIP.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TOLLIPprotein.

Applications:

WB

Background:

Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity.

Burns K., Nat. Cell Biol. 2:346-351(2000).
Wiemann S., Genome Res. 11:422-435(2001).
Zhang G., J. Biol. Chem. 277:7059-7065(2002).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF