Product Datasheet  
TOLLIP Antibody  
Catalog Number: 35328  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q9H0E2
    NCBI Gene ID: 54472
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from Internal of human TOLLIP.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • adapter protein; FLJ33531; IL-1RAcPIP; TOLIP; toll interacting protein
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total TOLLIPprotein.
  • Applications：  
  • WB
  • Background：  
  • Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity.

    Burns K., Nat. Cell Biol. 2:346-351(2000).
    Wiemann S., Genome Res. 11:422-435(2001).
    Zhang G., J. Biol. Chem. 277:7059-7065(2002).



 
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