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APOE Antibody

Catalog Number:

35301
other_names: AD2; Apo-E; APOE; Apolipoprotein E; apolipoprotein E3

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P02649
NCBI Gene ID: 348

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from C-terminal of human APOE.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total APOE protein.

Applications:

WB

Background:

Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.

Zannis V.I., J. Biol. Chem. 259:5495-5499(1984).
McLean J.W., J. Biol. Chem. 259:6498-6504(1984).
Paik Y.-K., Proc. Natl. Acad. Sci. U.S.A. 82:3445-3449(1985).

References:

appl_detail:

Western blotting: 1:500~1:3000

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