Product Datasheet
APOE Antibody
Catalog Number: 35301
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P02649
NCBI Gene ID: 348
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from C-terminal of human APOE.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- AD2; Apo-E; APOE; Apolipoprotein E; apolipoprotein E3
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total APOE protein.
- Background:
- Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
Zannis V.I., J. Biol. Chem. 259:5495-5499(1984).
McLean J.W., J. Biol. Chem. 259:6498-6504(1984).
Paik Y.-K., Proc. Natl. Acad. Sci. U.S.A. 82:3445-3449(1985).
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