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IRAK2 Antibody

Catalog Number:

35287
other_names: interleukin-1 receptor associated kinase-2; interleukin-1 receptor-associated kinase 2; Interleukin-1 receptor-associated kinase-like 2; IRAK-2; IRAK2

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: O43187
NCBI Gene ID: 3656

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from Internal of human IRAK2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total IRAK2 protein.

Applications:

WB

Background:

Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.

Rosati O., Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Muzio M., Science 278:1612-1615(1997).
Wesche H., J. Biol. Chem. 274:19403-19410(1999).

References:

appl_detail:

Western blotting: 1:500~1:3000

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