Product Datasheet
IRAK2 Antibody
Catalog Number: 35287
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: O43187
NCBI Gene ID: 3656
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from Internal of human IRAK2.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- interleukin-1 receptor associated kinase-2; interleukin-1 receptor-associated kinase 2; Interleukin-1 receptor-associated kinase-like 2; IRAK-2; IRAK2
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total IRAK2 protein.
- Background:
- Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
Rosati O., Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Muzio M., Science 278:1612-1615(1997).
Wesche H., J. Biol. Chem. 274:19403-19410(1999).
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