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BAG4 Antibody

Catalog Number:

35277
other_names: BAG family molecular chaperone regulator 4; BAG-4; BAG-family molecular chaperone regulator-4; BAG4; Bcl-2-associated athanogene 4

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: O95429
NCBI Gene ID: 9530

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from C-terminal of human BAG4.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total BAG4protein.

Applications:

WB

Background:

Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release By similarity. Prevents constitutive TNFRSF1A signaling. Negative regulator of PARK2 translocation to damaged mitochondria.

Takayama S., J. Biol. Chem. 274:781-786(1999).
Jiang Y., Science 283:543-546(1999).
Briknarova K., J. Biol. Chem. 277:31172-31178(2002).

References:

appl_detail:

Western blotting: 1:500~1:3000

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