Product Datasheet
BAG4 Antibody
Catalog Number: 35277
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: O95429
NCBI Gene ID: 9530
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from C-terminal of human BAG4.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- BAG family molecular chaperone regulator 4; BAG-4; BAG-family molecular chaperone regulator-4; BAG4; Bcl-2-associated athanogene 4
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total BAG4protein.
- Background:
- Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release By similarity. Prevents constitutive TNFRSF1A signaling. Negative regulator of PARK2 translocation to damaged mitochondria.
Takayama S., J. Biol. Chem. 274:781-786(1999).
Jiang Y., Science 283:543-546(1999).
Briknarova K., J. Biol. Chem. 277:31172-31178(2002).
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