Cytochrome P450 4A11/22 Antibody

Catalog Number:

35260

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q02928/Q5TCH4
NCBI Gene ID: 1579/284541

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human CYTOCHROME P450 4A11/22.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CYTOCHROME P450 4A11/22 protein.

Applications:

WB

Background:

Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate, myristate and palmitate. Has little activity toward prostaglandins A1 and E1. Oxidizes arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE).

Capdevila J.H., Arch. Biochem. Biophys. 409:221-227(2003).
Bentley D.R., Nature 441:315-321(2006).
Shin H.D., J. Hum. Genet. 50:259-263(2005).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF