Product Datasheet
Cytochrome P450 4A11/22 Antibody
Catalog Number: 35260
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q02928/Q5TCH4
NCBI Gene ID: 1579/284541
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human CYTOCHROME P450 4A11/22.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- CYP4A11 protein;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total CYTOCHROME P450 4A11/22 protein.
- Background:
- Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate, myristate and palmitate. Has little activity toward prostaglandins A1 and E1. Oxidizes arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE).
Capdevila J.H., Arch. Biochem. Biophys. 409:221-227(2003).
Bentley D.R., Nature 441:315-321(2006).
Shin H.D., J. Hum. Genet. 50:259-263(2005).
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