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CC14A Antibody

Catalog Number:

35243
other_names: CC14A; CDC10 (cell division cycle 10; S. cerevisiae; homolog); cdc14

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9UNH5
NCBI Gene ID: 8556

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from Internal of human CC14A.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CC14A protein.

Applications:

WB

Background:

Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis.

Li L., J. Biol. Chem. 272:29403-29406(1997).
Wong A.K.C., Genomics 59:248-251(1999).
Gregory S.G., Nature 441:315-321(2006).

References:

appl_detail:

Western blotting: 1:500~1:3000

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