Product Datasheet
CC14A Antibody
Catalog Number: 35243
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9UNH5
NCBI Gene ID: 8556
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from Internal of human CC14A.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- CC14A; CDC10 (cell division cycle 10; S. cerevisiae; homolog); cdc14
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total CC14A protein.
- Background:
- Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis.
Li L., J. Biol. Chem. 272:29403-29406(1997).
Wong A.K.C., Genomics 59:248-251(1999).
Gregory S.G., Nature 441:315-321(2006).
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