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SNIP Antibody

Catalog Number:

35235
other_names: p130Cas-associated protein; P140; p140Cap; SNAP-25-interacting protein;

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9C0H9
NCBI Gene ID: 80725

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human SNIP.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SNIP protein.

Applications:

WB

Background:

Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance.

Oka M., Submitted (DEC-2003).
Sugano S., Nat. Genet. 36:40-45(2004).
Ohara O., DNA Res. 7:347-355(2000).

References:

appl_detail:

Western blotting: 1:500~1:3000

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