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Catalog Number: |
35235 |
| other_names: | p130Cas-associated protein; P140; p140Cap; SNAP-25-interacting protein; |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot: Q9C0H9 |
Form of Antibody: |
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Storage/Stability: |
|
Immunogen: |
Synthesized peptide derived from internal of human SNIP. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total SNIP protein. |
Applications: |
WB |
Background: |
Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance. |
References: |
|
appl_detail: |
Western blotting: 1:500~1:3000 |
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