Product Datasheet
SNIP Antibody
Catalog Number: 35235
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9C0H9
NCBI Gene ID: 80725
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human SNIP.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- p130Cas-associated protein; P140; p140Cap; SNAP-25-interacting protein;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total SNIP protein.
- Background:
- Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance.
Oka M., Submitted (DEC-2003).
Sugano S., Nat. Genet. 36:40-45(2004).
Ohara O., DNA Res. 7:347-355(2000).
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