Cytochrome P450 11B1/2 Antibody

Catalog Number:

35212

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P15538/P19099
NCBI Gene ID: 1584/1585

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from C-terminal of human Cytochrome P450 11B1/2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Cytochrome P450 11B1/2 protein.

Applications:

WB

Background:

Has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB.

Mornet E., J. Biol. Chem. 264:20961-20967(1989).
Kawamoto T., FEBS Lett. 269:345-349(1990).
Nusbaum C., Nature 439:331-335(2006).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF