Product Datasheet  
Cytochrome P450 11B1/2 Antibody  
Catalog Number: 35212  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P15538/P19099
    NCBI Gene ID: 1584/1585
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from C-terminal of human Cytochrome P450 11B1/2.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • C11B1; CPN1; CYP11B; CYP11B1; CYPXIB1
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total Cytochrome P450 11B1/2 protein.
  • Applications：  
  • WB
  • Background：  
  • Has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB.

    Mornet E., J. Biol. Chem. 264:20961-20967(1989).
    Kawamoto T., FEBS Lett. 269:345-349(1990).
    Nusbaum C., Nature 439:331-335(2006).




 
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