WASF2 Antibody

Catalog Number:

35147

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9Y6W5
NCBI Gene ID: 10163

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human WASF2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total WASF2 protein.

Applications:

WB IHC

Background:

Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.

Suetsugu S., Biochem. Biophys. Res. Commun. 260:296-302(1999).
Gregory S.G., Nature 441:315-321(2006).
Miki H., Nature 408:732-735(2000).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF