Product Datasheet  
WASF2 Antibody  
Catalog Number: 35147  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q9Y6W5
    NCBI Gene ID: 10163
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human WASF2.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • Wiskott-Aldrich syndrome protein family member 2WASP family protein member 2; Protein WAVE-2; Verprolin homology domain-containing protein 2; WASF2;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total WASF2 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.

    Suetsugu S., Biochem. Biophys. Res. Commun. 260:296-302(1999).
    Gregory S.G., Nature 441:315-321(2006).
    Miki H., Nature 408:732-735(2000).



 
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