WIPF1 Antibody

Catalog Number:

35146

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O43516
NCBI Gene ID: 7456

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from C-terminal of human WIPF1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total WIPF1 protein.

Applications:

WB

Background:

Plays a role in the reorganization of the actin cytoskeleton. Contributes with NCK1 and GRB2 in the recruitment and activation of WASL. May participate in regulating the subcellular localization of WASL, resulting in the disassembly of stress fibers in favor of filopodia formation. Plays a role in the formation of cell ruffles By similarity. Plays an important role in the intracellular motility of vaccinia virus by functioning as an adapter for recruiting WASL to vaccinia virus.

Ramesh N., Proc. Natl. Acad. Sci. U.S.A. 94:14671-14676(1997).
Kreideweiss S., Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases.
Bechtel S., BMC Genomics 8:399-399(2007).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF