Product Datasheet  
WIPF1 Antibody  
Catalog Number: 35146  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O43516
    NCBI Gene ID: 7456
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from C-terminal of human WIPF1.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • WAS/WASL-interacting protein family member 1; Wiskott-Aldrich syndrome protein-interacting protein; WASP-interacting protein; PRPL-2 protein; WIPF1
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total WIPF1 protein.
  • Applications：  
  • WB
  • Background：  
  • Plays a role in the reorganization of the actin cytoskeleton. Contributes with NCK1 and GRB2 in the recruitment and activation of WASL. May participate in regulating the subcellular localization of WASL, resulting in the disassembly of stress fibers in favor of filopodia formation. Plays a role in the formation of cell ruffles By similarity. Plays an important role in the intracellular motility of vaccinia virus by functioning as an adapter for recruiting WASL to vaccinia virus.

    Ramesh N., Proc. Natl. Acad. Sci. U.S.A. 94:14671-14676(1997).
    Kreideweiss S., Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases.
    Bechtel S., BMC Genomics 8:399-399(2007).



 
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