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NSF Antibody

Catalog Number:

35142
other_names: Vesicle-fusing ATPase; EC=3.6.4.6; N-ethylmaleimide-sensitive fusion protein; Short name=NEM-sensitive fusion protein; Vesicular-fusion protein NSF

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P46459
NCBI Gene ID: 4905

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human NSF.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NSF protein.

Applications:

WB

Background:

Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling By similarity.

Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].
Zody M.C., Nature 440:1045-1049(2006) [PubMed: 16625196] [Abstract].

References:

appl_detail:

Western blotting: 1:500~1:3000

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