Product Datasheet  
NSF Antibody  
Catalog Number: 35142  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P46459
    NCBI Gene ID: 4905
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human NSF.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • Vesicle-fusing ATPase; EC=3.6.4.6; N-ethylmaleimide-sensitive fusion protein; Short name=NEM-sensitive fusion protein; Vesicular-fusion protein NSF
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total NSF protein.
  • Applications：  
  • WB
  • Background：  
  • Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling By similarity.

    Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].
    Zody M.C., Nature 440:1045-1049(2006) [PubMed: 16625196] [Abstract].




 
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