USP6NL Antibody

Catalog Number:

35136

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q92738
NCBI Gene ID: 9712

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human USP6NL.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total USP6NL protein.

Applications:

IHC

Background:

Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.

Wong W.T., Oncogene 12:2563-2571(1996).
Nomura N., DNA Res. 1:27-35(1994).
Lanzetti L., Nature 408:374-377(2000)

References:

appl_detail:

Immunohistochemistry: 1:50~1:100

Datasheet PDF