Product Datasheet  
USP6NL Antibody  
Catalog Number: 35136  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q92738
    NCBI Gene ID: 9712
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human USP6NL.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1:50~1:100
  • other_names：  
  • USP6 N-terminal-like protein; Related to the N-terminus of tre; RN-tre; USP6NL; KIAA0019
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total USP6NL protein.
  • Applications：  
  • IHC
  • Background：  
  • Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.

    Wong W.T., Oncogene 12:2563-2571(1996).
    Nomura N., DNA Res. 1:27-35(1994).
    Lanzetti L., Nature 408:374-377(2000)



 
© Signalway Biotechnology All Rights Reserved.