TCF4/12 Antibody

Catalog Number:

35102

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P15884/Q99081
NCBI Gene ID: 6925/6938

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human TCF4/12.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TCF4/12 protein.

Applications:

WB

Background:

Transcription factor that binds to the immunoglobulin enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription By similarity. Preferentially binds to either 5'-ACANNTGT-3' or 5'-CCANNTGG-3'.

Corneliussen B., J. Virol. 65:6084-6093(1991).
Breschel T.S., Hum. Mol. Genet. 6:1855-1863(1997).
Amiel J., Am. J. Hum. Genet. 80:988-993(2007).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF