Product Datasheet  
TCF4/12 Antibody  
Catalog Number: 35102  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P15884/Q99081
    NCBI Gene ID: 6925/6938
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human TCF4/12.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • Class A helix-loop-helix transcription factor ME2; ITF-2; ITF2; Immunoglobulin transcription factor 2; MITF-2
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total TCF4/12 protein.
  • Applications：  
  • WB
  • Background：  
  • Transcription factor that binds to the immunoglobulin enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription By similarity. Preferentially binds to either 5'-ACANNTGT-3' or 5'-CCANNTGG-3'.

    Corneliussen B., J. Virol. 65:6084-6093(1991).
    Breschel T.S., Hum. Mol. Genet. 6:1855-1863(1997).
    Amiel J., Am. J. Hum. Genet. 80:988-993(2007).



 
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