SCN9A Antibody

Catalog Number:

35056

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q15858
NCBI Gene ID: 6335

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human SCN9A.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SCN9A protein.

Applications:

WB IHC

Background:

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na+ channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain By similarity.

Klugbauer N., EMBO J. 14:1084-1090(1995).
Cox J.J., Nature 444:894-898(2006).
Raymond C.K., J. Biol. Chem. 279:46234-46241(2004).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF