Product Datasheet  
SCN9A Antibody  
Catalog Number: 35056  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q15858
    NCBI Gene ID: 6335
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human SCN9A.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • Sodium channel protein type 9 subunit alpha; Sodium channel protein type IX subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.7; Neuroendocrine sodium channel; hNE-Na
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total SCN9A protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na+ channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain By similarity.

    Klugbauer N., EMBO J. 14:1084-1090(1995).
    Cox J.J., Nature 444:894-898(2006).
    Raymond C.K., J. Biol. Chem. 279:46234-46241(2004).



 
© Signalway Biotechnology All Rights Reserved.