ARHGEF11 Antibody

Catalog Number:

34991

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O15085
NCBI Gene ID: 9826

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from N-terminal of human ARHGEF11.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ARHGEF11 protein.

Applications:

WB

Background:

May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth.

Nagase T., DNA Res. 4:141-150(1997).
Gregory S.G., Nature 441:315-321(2006).
Ruemenapp U., FEBS Lett. 459:313-318(1999).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF