Product Datasheet  
ARHGEF11 Antibody  
Catalog Number: 34991  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O15085
    NCBI Gene ID: 9826
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from N-terminal of human ARHGEF11.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • ARHGB; glutamate transporter EAAT4-associated protein 48; GTRAP48; PDZ-RhoGEF; rho guanine exchange factor (GEF) 11
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total ARHGEF11 protein.
  • Applications：  
  • WB
  • Background：  
  • May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth.

    Nagase T., DNA Res. 4:141-150(1997).
    Gregory S.G., Nature 441:315-321(2006).
    Ruemenapp U., FEBS Lett. 459:313-318(1999).



 
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