PTPRZ1 Antibody

Catalog Number:

34977

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P23471
NCBI Gene ID: 5803

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from N-terminal of human PTPRZ1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PTPRZ1 protein.

Applications:

WB

Background:

Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades By similarity.

Krueger N.X., Proc. Natl. Acad. Sci. U.S.A. 89:7417-7421(1992).
Levy J.B., J. Biol. Chem. 268:10573-10581(1993).
Hillier L.W., Nature 424:157-164(2003).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF