Product Datasheet  
PTPRZ1 Antibody  
Catalog Number: 34977  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot: P23471
    NCBI Gene ID: 5803
  • Form of Antibody:  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthesized peptide derived from N-terminal of human PTPRZ1.
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:500~1:3000

  • other_names:  
  • R-PTP-zeta; Protein-tyrosine phosphatase receptor type Z polypeptide 1;
  • Purification:  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity:  
  • The antibody detects endogenous levels of total PTPRZ1 protein.
  • Applications:  
  • WB
  • Background:  
  • Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades By similarity.

    Krueger N.X., Proc. Natl. Acad. Sci. U.S.A. 89:7417-7421(1992).
    Levy J.B., J. Biol. Chem. 268:10573-10581(1993).
    Hillier L.W., Nature 424:157-164(2003).



 
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