SLCO1B1 Antibody

Catalog Number:

35068

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9Y6L6
NCBI Gene ID: 10599

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human SLCO1B1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SLCO1B1 protein.

Applications:

WB

Background:

Mediates the Na+-independent uptake of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. Involved in the clearance of bile acids and organic anions from the liver.

Kirchgessner T.G., J. Biol. Chem. 274:37161-37168(1999).
Keppler D., J. Biol. Chem. 275:23161-23168(2000).
Venter J.C., Submitted (JUL-2005).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF