Product Datasheet  
SLCO1B1 Antibody  
Catalog Number: 35068  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q9Y6L6
    NCBI Gene ID: 10599
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human SLCO1B1.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • Solute carrier family 21 member 6; Sodium-independent organic anion-transporting polypeptide 2; OATP 2; Liver-specific organic anion transporter 1; LST-1
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total SLCO1B1 protein.
  • Applications：  
  • WB
  • Background：  
  • Mediates the Na+-independent uptake of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. Involved in the clearance of bile acids and organic anions from the liver.

    Kirchgessner T.G., J. Biol. Chem. 274:37161-37168(1999).
    Keppler D., J. Biol. Chem. 275:23161-23168(2000).
    Venter J.C., Submitted (JUL-2005).



 
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