RAB3GAP2 Antibody

Catalog Number:

34951

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9H2M9
NCBI Gene ID: 25782

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total RAB3GAP2 protein.

Applications:

WB IHC

Background:

Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.

Nagano F., J. Biol. Chem. 273:24781-24785(1998).
Xu X., Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
Nagase T., DNA Res. 5:355-364(1998).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF