Product Datasheet  
RAB3GAP2 Antibody  
Catalog Number: 34951  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q9H2M9
    NCBI Gene ID: 25782
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • RAB3 GTPase activating protein 2 (non-catalytic); RAB3-GAP150; RAB3GAP150; RBGPR; RGAP-iso
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total RAB3GAP2 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.

    Nagano F., J. Biol. Chem. 273:24781-24785(1998).
    Xu X., Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
    Nagase T., DNA Res. 5:355-364(1998).



 
© Signalway Biotechnology All Rights Reserved.