RAB11FIP3 Antibody

Catalog Number:

34950

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O75154
NCBI Gene ID: 9727

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from C-terminal of human RAB11FIP3.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total RAB11FIP3 protein.

Applications:

IHC

Background:

Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton.

Prekeris R., J. Biol. Chem. 276:38966-38970(2001).
Ishikawa K., DNA Res. 5:169-176(1998).
Daniels R.J., Hum. Mol. Genet. 10:339-352(2001).

References:

appl_detail:

Immunohistochemistry: 1:50~1:100

Datasheet PDF