Product Datasheet  
RAB11FIP3 Antibody  
Catalog Number: 34950  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O75154
    NCBI Gene ID: 9727
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from C-terminal of human RAB11FIP3.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1:50~1:100
  • other_names：  
  • Rab11-FIP3; EF hands-containing Rab-interacting protein; Eferin;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total RAB11FIP3 protein.
  • Applications：  
  • IHC
  • Background：  
  • Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton.

    Prekeris R., J. Biol. Chem. 276:38966-38970(2001).
    Ishikawa K., DNA Res. 5:169-176(1998).
    Daniels R.J., Hum. Mol. Genet. 10:339-352(2001).




 
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