OAZ1 Antibody

Catalog Number:

34883

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P54368
NCBI Gene ID: 4946

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from N-terminal of human OAZ1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total OAZ1 protein.

Applications:

IHC

Background:

Binds to, and destabilizes, ornithine decarboxylase which is then degraded. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.

Tewari D.S., Biochim. Biophys. Acta 1209:293-295(1994).
Hideyama T., Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases.
Yang D., Biochem. Mol. Biol. Int. 38:957-964(1996).

References:

appl_detail:

Immunohistochemistry: 1:50~1:100

Datasheet PDF