Product Datasheet  
OAZ1 Antibody  
Catalog Number: 34883  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P54368
    NCBI Gene ID: 4946
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from N-terminal of human OAZ1.
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  • Immunohistochemistry: 1:50~1:100
  • other_names：  
  • Ornithine decarboxylase antizyme; ODC-Az;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total OAZ1 protein.
  • Applications：  
  • IHC
  • Background：  
  • Binds to, and destabilizes, ornithine decarboxylase which is then degraded. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.

    Tewari D.S., Biochim. Biophys. Acta 1209:293-295(1994).
    Hideyama T., Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases.
    Yang D., Biochem. Mol. Biol. Int. 38:957-964(1996).



 
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